HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Ansgar Brüning Selected Research

Nelfinavir (Viracept)

12/2013Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation.
10/2012Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4.
9/2011Targeting the off-targets: a computational bioinformatics approach to understanding the polypharmacology of nelfinavir.
1/2011Analysis of nelfinavir-induced endoplasmic reticulum stress.
10/2010Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib.
6/2010New prospects for nelfinavir in non-HIV-related diseases.
1/2010The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization.
1/2010Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.
2/2009Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis.
12/2008Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Ansgar Brüning Research Topics

Disease

34Neoplasms (Cancer)
01/2017 - 08/2004
12Ovarian Neoplasms (Ovarian Cancer)
07/2014 - 09/2005
8Uterine Cervical Neoplasms (Cancer of the Cervix)
11/2014 - 08/2004
8Carcinoma (Carcinomatosis)
10/2011 - 07/2009
6Breast Neoplasms (Breast Cancer)
12/2014 - 01/2010
6Adenocarcinoma
10/2011 - 06/2005
5Carcinogenesis
10/2011 - 10/2009
5Endometrial Neoplasms (Endometrial Cancer)
07/2011 - 05/2009
3Leukemia
01/2017 - 01/2010
3Neoplasm Metastasis (Metastasis)
12/2014 - 09/2008
3Endometrioid Carcinoma
07/2011 - 05/2010
2Glioblastoma (Glioblastoma Multiforme)
01/2016 - 04/2013
2Ascites
02/2009 - 09/2005
1Hyperthermia
01/2015
1Communicable Diseases (Infectious Diseases)
01/2014
1Reperfusion Injury
11/2013
1Hepatocellular Carcinoma (Hepatoma)
10/2012
1Hepatoblastoma
10/2012
1Fetal Growth Retardation (Intrauterine Growth Retardation)
08/2011
1Hemolysis
08/2011

Drug/Important Bio-Agent (IBA)

16Pharmaceutical PreparationsIBA
01/2015 - 12/2008
11Inhibins (Inhibin)IBA
10/2012 - 05/2009
10Nelfinavir (Viracept)FDA Link
12/2013 - 12/2008
8Proteins (Proteins, Gene)FDA Link
01/2017 - 06/2005
8Activins (Activin)IBA
07/2011 - 05/2009
6HIV Protease InhibitorsIBA
01/2011 - 12/2008
5DNA (Deoxyribonucleic Acid)IBA
01/2017 - 05/2011
4Proteasome InhibitorsIBA
10/2016 - 02/2009
4Cadherins (E-Cadherin)IBA
12/2014 - 08/2004
4Estrogen ReceptorsIBA
12/2014 - 09/2005
4Hormones (Hormone)IBA
12/2014 - 09/2005
3CaspasesIBA
01/2017 - 09/2005
3AnnexinsIBA
01/2017 - 12/2008
3Bortezomib (Velcade)FDA Link
10/2016 - 12/2009
3CytokinesIBA
01/2016 - 09/2008
3Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2015 - 06/2010
3Drug CombinationsIBA
02/2013 - 01/2010
3Peptide Hormones (Polypeptide Hormones)IBA
10/2011 - 10/2010
3Carboplatin (JM8)FDA LinkGeneric
05/2011 - 02/2009
3Estrogen Receptor alphaIBA
11/2010 - 09/2008
2NucleosidesIBA
01/2017 - 10/2012
2RNA (Ribonucleic Acid)IBA
01/2017 - 10/2012
2Proteasome Endopeptidase Complex (Proteasome)IBA
10/2016 - 01/2012
2EnzymesIBA
12/2014 - 08/2011
2Histones (Histone)IBA
12/2014 - 10/2012
2Pemetrexed (MTA)FDA Link
12/2014 - 07/2009
2Tumor Biomarkers (Tumor Markers)IBA
07/2014 - 08/2011
2Disulfiram (Antabuse)FDA Link
01/2014 - 01/2014
2Biological ProductsIBA
04/2013 - 01/2012
2Doxorubicin (Adriamycin)FDA LinkGeneric
08/2012 - 05/2011
2inhibin beta A subunitIBA
10/2011 - 05/2009
2Sorafenib (BAY 43-9006)FDA Link
10/2010 - 01/2010
2LigandsIBA
12/2009 - 06/2005
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
12/2009 - 12/2008
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2009 - 06/2005
2GlucocorticoidsIBA
08/2006 - 09/2005
1Reverse Transcriptase InhibitorsIBA
01/2017
1efavirenz (Sustiva)FDA Link
01/2017
1ProteomeIBA
01/2015
1Oncogene Proteins (Oncogene Protein)IBA
01/2015
1Cytostatic AgentsIBA
01/2015
1MacrolidesIBA
10/2014
1borrelidinIBA
10/2014
1Anti-Bacterial Agents (Antibiotics)IBA
10/2014
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2014
1Biomarkers (Surrogate Marker)IBA
07/2014
1TetracyclinesIBA
01/2014
1ThioredoxinsIBA
01/2014
1disulfiram-copperIBA
01/2014
1Auranofin (Ridaura)FDA Link
01/2014
1CopperIBA
01/2014
1Temozolomide (Temodar)FDA LinkGeneric
04/2013
1ElementsIBA
04/2013
1ThapsigarginIBA
10/2012
1TunicamycinIBA
10/2012
1cordycepinIBA
10/2012
1CytidineIBA
08/2012
1Tenofovir (Viread)FDA Link
08/2012
1Tenofovir Disoproxil Fumarate Drug Combination EmtricitabineFDA Link
08/2012
1Emtricitabine (Emtriva)FDA Link
08/2012
1DNA Repair EnzymesIBA
08/2012
1HIV Reverse TranscriptaseIBA
08/2012
1Adenosine (Adenocard)FDA LinkGeneric
08/2012
1FlavonoidsIBA
01/2012
1AntioxidantsIBA
01/2012
1Phosphotransferases (Kinase)IBA
01/2012
1QuercetinIBA
01/2012
1DNA ProbesIBA
10/2011
1Inhibin-beta SubunitsIBA
10/2011
1GemcitabineFDA Link
05/2011
1AntibodiesIBA
05/2011
1Topotecan (Hycamtin)FDA LinkGeneric
05/2011
1Oxaliplatin (Eloxatin)FDA LinkGeneric
05/2011
1Epothilones (Epothilone)IBA
05/2011
1Taxoids (Taxanes)IBA
05/2011
1Transcription Factors (Transcription Factor)IBA
11/2010

Therapy/Procedure

4Therapeutics
01/2016 - 03/2010
4Drug Therapy (Chemotherapy)
01/2015 - 09/2005
1Hepatectomy
11/2013
1Cesarean Section (Caesarean Section)
08/2011